姓名

霍贵成

性别

男

职称

教授

所在系别

乳品工程系

电子邮箱

学习

经历

1981年本科毕业于河北农业大学畜牧系畜牧专业，硕士研究生毕业于东北农学院畜牧系动物营养专业。

1984年硕士毕业后留任东北农学院动物营养研究室任助理研究员。

1988年博士研究生毕业于东北农学院畜牧系动物营养专业

社会

兼职

教学

成果

主要研究方向为营养与乳品加工，重点研究领域有乳制品质量安全控制与检测技术研究，乳酸菌代谢功能与发酵剂开发，婴儿营养与配方粉开发及乳制品多样化。在“十五”、“十一五”和“十二五”期间围绕乳品加工及质量和安全控制主持国家科技支撑项目、863项目、国家自然科学平台项目、国家自然基金项目、农业科技成果转化项目及省部级课题共计23项。获得省级科技发明一等奖1项，科技进步二、三等奖3项，中国高校科技进步二等奖1项，获得11项国家发明专利授权。共发表298篇论文，其中SCI论文25篇。转让专利成果2项，开发出原料奶细菌总数快速检测仪，体细胞快速检测仪，低温浓缩和低温喷雾设备，奶酪拉伸机和成型机，移动式乳品加工车，上述设备均产业化。截止目前，培养毕业培养出博士研究生47名，硕士研究生108名。

科研

成果

国家重点研发计划项目：益生菌健康功能与基于肠道微生物组学的食品营养代谢机理研究。2017-2020年，国拨经费570万元

授权发明专利，专利号：ZL 201510044052.3 专利名称：一株具有低b-半乳糖酶活性的德氏乳杆菌保加利亚亚种菌株及其应用，发明人：霍贵成曹凤波等，授予时间：2017年10月31日。

授权发明专利，专利号：ZL 201410835326.6 专利名称：一种高产细菌素粪肠球菌及其应用，发明人：霍贵成王雪芹 杨丽杰，授予时间：2017年12月15日。

1、Bailiang Li, Fei Liu, Yaru Tang, Guangwen Luo, Smith Evivie, Danqing Zhang, Nana Wang, Wan Li, Guicheng Huo*. Complete genome sequence of Lactobacillus helveticus KLDS1.8701, a probiotic strain producing bacteriocin, Journal of Biotechnology, 2015, 212：90-91。

2、Guo, L., Li, T., Tang, Y., Yang, L. and Huo, G*. Probiotic properties of Enterococcus strains isolated from traditional naturally fermented cream in China. Microbial Biotechnology. 2015, doi: 10.1111/1751-7915.12306

3、Bian, X., Huo, G*., Evivie, S.E., Muhammad, Z., Luo, G.-w., Liang, H.-z., and Wang, N.-n. In vitro Assessment of Antimicrobial Potentials of Lactobacillus helveticus Strains Isolated from Traditional Cheese in Sinkiang China against Food-borne Pathogens,Food & Function. 2015, DOI: 10.1039/C5FO01041A

4、Fei Liu, Bailiang Li, Jincheng Du, Shangfu Yu, Wan Li, Smith Evivie, Lidong Guo, Xiuyun Ding, Min Xu, Guicheng Huo*. Complete genome sequence of Enterococcus durans KLDS6.0930, a strain with probiotic properties. J. Biotechnol. 2015, http://dx.doi.org/10.1016/j.jbiotec.2015.11.012

5、Bian, X., Evivie, S. E., Muhammad, Z., Luo, G. W., Liang, H. Z., Wang, N. N., & Huo, G. C. (2016). In vitro assessment of the antimicrobial potentials of Lactobacillus helveticus strains isolated from traditional cheese in Sinkiang China against food-borne pathogens. Food & function, 7(2), 789-797.

6、Bian, X., Muhammad, Z., Evivie, S. E., Luo, G. W., Xu, M., & Huo, G. C. (2016). Screening of antifungal potentials of Lactobacillus helveticus KLDS 1.8701 against spoilage microorganism and their effects on physicochemical properties and shelf life of fermented soybean milk during preservation. Food Control, 66, 183-189./

7、Li, W., Bian, X., Evivie, S. E., & Huo, G. C. (2016). Comparative Analysis of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) of Streptococcus thermophilus St-I and its Bacteriophage-Insensitive Mutants (BIM) Derivatives. Current microbiology, 73(3), 393-400.

8、Bian, X., Wang, T. T., Xu, M., Evivie, S. E., Luo, G. W., Liang, H. Z., ... & Huo, G. C. (2016). Effect of Lactobacillus strains on intestinal microflora and mucosa immunity in Escherichia coli O157: H7-induced diarrhea in mice. Current microbiology, 73(1), 65-70.

9、Liu, F., Li, B., Du, J., Yu, S., Li, W., Evivie, S. E., ... & Huo, G. (2016). Complete genome sequence of Enterococcus durans KLDS6. 0930, a strain with probiotic properties. Journal of biotechnology, 217, 49-50.

10、Muhammad, Z., Ramzan, R., Huo, G. C., Tian, H., & Bian, X. (2017). Integration of polysaccharide-thermoprotectant formulations for microencapsulation of Lactobacillus plantarum, appraisal of survivability and physico-biochemical properties during storage of spray dried powders. Food hydrocolloids, 66, 286-295.

11、Li, B., Jin, D., Yu, S., Etareri Evivie, S., Muhammad, Z., Huo, G., & Liu, F. (2017). In Vitro and In Vivo Evaluation of Lactobacillus delbrueckii subsp. bulgaricus KLDS1. 0207 for the Alleviative Effect on Lead Toxicity. Nutrients, 9(8), 845.

12、Evivie, S. E., Li, B., Ding, X., Meng, Y., Yu, S., ... Huo, G., & Liu, F. (2017). Complete Genome Sequence of Streptococcus thermophilus KLDS 3.1003, A Strain with High Antimicrobial Potential against Foodborne and Vaginal Pathogens. Frontiers in microbiology, 8, 1238.

13、Li, B., Jin, D., Etareri Evivie, S., Li, N., Yan, F., Zhao, L., ... & Huo, G. (2017). Safety Assessment of Lactobacillus helveticus KLDS1. 8701 Based on Whole Genome Sequencing and Oral Toxicity Studies. Toxins, 9(10), 301.

14、Tian, H., Muhammad, Z., Evivie, S. E., Gu, C. T., & Huo, G. C. (2017). Exact identification of six starter‐strain candidates of Streptococcus thermophilus by analysing genotypic and industrial properties. International Journal of Dairy Technology.

15、Evivie, S. E., Huo, G. C., Igene, J. O., & Bian, X. (2017). Some current applications, limitations and future perspectives of lactic acid bacteria as probiotics. Food & nutrition research, 61(1), 1318034.

16、Fan, W., Ren, H., Cao, Y., Wang, Y., & Huo, G. (2017). Low dietary protein and high carbohydrate infant formula affects the microbial ecology of the large intestine in neonatal rats. Canadian journal of microbiology, 63(12), 951-960

奖励

荣誉

2014年度黑龙江省科技发明奖一等奖，黑龙江省人民政府，第一名